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Sphingosine-1-phosphate receptor : ウィキペディア英語版 | Sphingosine-1-phosphate receptor The sphingosine-1-phosphate receptors are a class of G protein-coupled receptors that are targets of the lipid signalling molecule Sphingosine-1-phosphate (S1P). They are divided into five subtypes: S1PR1, S1PR2, S1PR3, S1PR4 and S1PR5. == Discovery == In 1990, S1PR1 was the first member of the S1P receptor family to be cloned from endothelial cells. Later, S1PR2 and S1PR3 were cloned from rat brain and a human genomic library respectively. Finally, S1P4 and S1PR5 were cloned from in vitro differentiated human dendritic cells and rat cDNA library.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Sphingosine-1-phosphate receptor」の詳細全文を読む
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